In 2012, Dyer played the lead role in Ray Cooney's Run For Your Wife.
Upon release in 2013, it was savaged by critics, who described it as one of the worst British films of all time.
Following the success of The Football Factory, Dyer was often typecast in "hard-man" roles, although it was this image that allowed him to present The Real Football Factories, its spin-off, The Real Football Factories International and Danny Dyer's Deadliest Men.
Dyer has also worked in theatre, having appeared in three plays written by Harold Pinter, with whom he had a close friendship.
On 1 October 2013, the BBC announced that Dyer had been cast in East Enders from Christmas 2013, as Mick Carter, the new landlord of The Queen Victoria pub.In 2013, he was announced as the latest addition to the cast of East Enders, playing Mick Carter, the most recent landlord of The Queen Victoria.He had previously turned down a role in 2009, and in his autobiography, Straight Up, said that he would not join the cast until he was "fat, bald and fifty".Dyer is the voice of Kent Paul in the video games Grand Theft Auto: Vice City (2002) and Grand Theft Auto: San Andreas (2004).I Believe in UFOS: Danny Dyer, a documentary that sees Dyer journey to various "UFO hotspots" in the UK and the US in hope of experiencing a UFO sighting, was broadcast on BBC Three on 26 January 2010.